Tumor Angiogenesis Change Estimated by Using Diffuse Optical Spectroscopic Tomography: Demonstrated Correlation in Women Undergoing Neoadjuvant Chemotherapy for Invasive Breast Cancer?

Tumor Angiogenesis Change Estimated by Using Diffuse Optical Spectroscopic Tomography: Demonstrated Correlation in Women Undergoing Neoadjuvant Chemotherapy for Invasive Breast Cancer?
Marius G. Pakalniskis, Wendy A. Wells, Mary C. Schwab, Heather M. Froehlich, Shudong Jiang, Zhongze Li, Tor D. Tosteson, Steven P. Poplack, Peter A. Kaufman, Brian W. Pogue, and Keith D. Paulsen
Radiology 2011; 259 365-374

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This study results show a correlation between changes in total tissue hemoglobin at diffuse optical spectroscopic tomography and tumor angiogenesis and demonstrate how this noninvasive modality might allow individualization and optimization of neoadjuvant chemotherapy regimens.

Evaluation of Clinical Breast MR Imaging Performed with Prototype Computer-aided Diagnosis Breast MR Imaging Workstation: Reader Study

Evaluation of Clinical Breast MR Imaging Performed with Prototype Computer-aided Diagnosis Breast MR Imaging Workstation: Reader Study
Akiko Shimauchi, Maryellen L. Giger, Neha Bhooshan, Li Lan, Lorenzo L. Pesce, John K. Lee, Hiroyuki Abe, and Gillian M. Newstead
Radiology 2011; 258 696-704

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Use of a diagnostic computer aid for dynamic contrast-enhanced MR imaging has the potential to improve radiologists' performance in differentiating between benign and malignant breast lesions

The Mammographic Density of a Mass Is a Significant Predictor of Breast Cancer

The Mammographic Density of a Mass Is a Significant Predictor of Breast Cancer
Ryan W. Woods, Gale S. Sisney, Lonie R. Salkowski, Kazuhiko Shinki, Yunzhi Lin, and Elizabeth S. Burnside
Radiology 2011; 258 417-425

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Our study shows that, in contrast to previous research, breast mass density is significantly associated with malignancy, even after controlling for other predictive variables

Breast Cancer: Early and Late Fluorescence Near-Infrared Imaging with Indocyanine Green: A Preliminary Study

Breast Cancer: Early and Late Fluorescence Near-Infrared Imaging with Indocyanine Green: A Preliminary Study
Alexander Poellinger, Susen Burock, Dirk Grosenick, Axel Hagen, Lutz Ludemann, Felix Diekmann, Florian Engelken, Rainer Macdonald, Herbert Rinneberg, and Peter-Michael Schlag
Radiology 2011; 258 409-416

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By capitalizing on the extravasation of indocyanine green (ICG) through the wall of tumorous vessels and consequently using late-fluorescence mammograms, we were able to achieve far more pronounced contrast between the tumorous and healthy background tissue (mean contrast value, 0.64) compared with this contrast on images acquired during or shortly after the administration of ICG (mean contrast value, 0.25)

Multicenter, Double-Blind, Randomized, Intraindividual Crossover Comparison of Gadobenate Dimeglumine and Gadopentetate Dimeglumine for Breast MR Imaging (DETECT Trial)

Multicenter, Double-Blind, Randomized, Intraindividual Crossover Comparison of Gadobenate Dimeglumine and Gadopentetate Dimeglumine for Breast MR Imaging (DETECT Trial)
Laura Martincich, Matthieu Faivre-Pierret, Christian M. Zechmann, Stefano Corcione, Harrie C. M. van den Bosch, Wei-Jun Peng, Antonella Petrillo, Katja C. Siegmann, Johannes T. Heverhagen, Pietro Panizza, Hans-Bjorn Gehl, Felix Diekmann, Federica Pediconi, Lin Ma, Fiona J. Gilbert, Francesco Sardanelli, Paolo Belli, Marco Salvatore, Karl-Friedrich Kreitner, Claudia M. Weiss, and Chiara Zuiani
Radiology 2011; 258 396-408

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Gadobenate dimeglumine (0.1 mmol/kg) results in significantly (P [≤ ] . 0003) greater breast cancer detection rate and significantly (P [≤ ] . 0094) better diagnostic performance relative to that achieved with gadopentetate dimeglumine at an equivalent dose

Reduction in False-Positive Results after Introduction of Digital Mammography: Analysis from Four Population-based Breast Cancer Screening Programs in Spain

Reduction in False-Positive Results after Introduction of Digital Mammography: Analysis from Four Population-based Breast Cancer Screening Programs in Spain
Maria Sala, Dolores Salas, Francesc Belvis, Mar Sanchez, Joana Ferrer, Josefa Ibanez, Ruben Roman, Francisco Ferrer, Alfonso Vega, Maria Soledad Laso, and Xavier Castells
Radiology 2011; 258 388-395

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While cancer detection did not differ in women screened with screen-film mammography (SFM) or digital mammography (DM), the recall rate and false-positive risk were lower with DM than with SFM after adjustment was made for the woman's screening mammogram, radiology unit screening round, age at screening, and time trends

Utility of 6-month Follow-up Imaging after a Concordant Benign Breast Biopsy Result

Utility of 6-month Follow-up Imaging after a Concordant Benign Breast Biopsy Result
Lonie R. Salkowski, Amy M. Fowler, Elizabeth S. Burnside, and Gale A. Sisney
Radiology 2011; 258 380-387

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Six-month follow-up imaging for benign image-guided core biopsy results assessed as concordant with consensus review did not aid detection of breast cancers or influence recommended rebiopsy rates, suggesting that yearly follow-up may be more appropriate