Comparison of Soft-copy and Hard-copy Reading for Full-Field Digital Mammography

Comparison of Soft-copy and Hard-copy Reading for Full-Field Digital Mammography
Robert M. Nishikawa, Suddhasatta Acharyya, Constantine Gatsonis, Etta D. Pisano, Elodia B. Cole, Helga S. Marques, Carl J. D'Orsi, Dione M. Farria, Kalpana M. Kanal, Mary C. Mahoney, Murray Rebner, Melinda J. Staiger For the Digital Mammography Image Screening Trial investigator group
Radiology 2009;251 41-49

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DMIST Reader Study findings -
In a large reader study, it was found that there was no advantage to soft-copy reading of full-field digital mammograms over digitally printed images

BUT the display formats were not optimized and display software remains an evolving process, particularly for soft-copy reading

Positive Predictive Value of Specific Mammographic Findings according to Reader and Patient Variables

Positive Predictive Value of Specific Mammographic Findings according to Reader and Patient Variables
Aruna Venkatesan, Philip Chu, Karla Kerlikowske, Edward A. Sickles, and Rebecca Smith-Bindman
Radiology 2009;250 648-657

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Another UCSF classic paper. Asymmetry is the finding with the lowest cancer yield at screening examinations; with asymmetry, invasive cancer (particularly among women younger than 70 years) was infrequently identified and was commonly a false-positive result

Triple-Negative Breast Cancer: Correlation between MR Imaging and Pathologic Findings

Triple-Negative Breast Cancer: Correlation between MR Imaging and Pathologic Findings
Takayoshi Uematsu, Masako Kasami, and Sachiko Yuen
Radiology 2009;250 638-647

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MR imaging findings of a unifocal lesion, mass lesion type, smooth mass margin, heterogeneous rim enhancement, persistent enhancement pattern, and very high signal intensity on T2-weighted images can be used to detect triple-negative breast cancer

Large-Core Breast Biopsy: Abnormal Salivary Cortisol Profiles Associated with Uncertainty of Diagnosis

Large-Core Breast Biopsy: Abnormal Salivary Cortisol Profiles Associated with Uncertainty of Diagnosis
Elvira V. Lang, Kevin S. Berbaum, and Susan K. Lutgendorf
Radiology 2009;250 631-637

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Uncertainty about the final diagnosis after LCBB is associated with substantial biochemical distress, which may have adverse effects on immune defense and wound healing. Results indicate the need for more rapid communication of biopsy results
Not only how but also when biopsy results become available to the patient is important to avoid the dysregulation of cortisol secretion, even if the results are benign