Multicenter, Double-Blind, Randomized, Intraindividual Crossover Comparison of Gadobenate Dimeglumine and Gadopentetate Dimeglumine for Breast MR Imaging (DETECT Trial)

Multicenter, Double-Blind, Randomized, Intraindividual Crossover Comparison of Gadobenate Dimeglumine and Gadopentetate Dimeglumine for Breast MR Imaging (DETECT Trial)
Laura Martincich, Matthieu Faivre-Pierret, Christian M. Zechmann, Stefano Corcione, Harrie C. M. van den Bosch, Wei-Jun Peng, Antonella Petrillo, Katja C. Siegmann, Johannes T. Heverhagen, Pietro Panizza, Hans-Bjorn Gehl, Felix Diekmann, Federica Pediconi, Lin Ma, Fiona J. Gilbert, Francesco Sardanelli, Paolo Belli, Marco Salvatore, Karl-Friedrich Kreitner, Claudia M. Weiss, and Chiara Zuiani
Radiology 2011; 258 396-408

Link to Journal

Gadobenate dimeglumine (0.1 mmol/kg) results in significantly (P [≤ ] . 0003) greater breast cancer detection rate and significantly (P [≤ ] . 0094) better diagnostic performance relative to that achieved with gadopentetate dimeglumine at an equivalent dose

Cancerous Breast Lesions on Dynamic Contrast-enhanced MR Images: Computerized Characterization for Image-based Prognostic Markers

Cancerous Breast Lesions on Dynamic Contrast-enhanced MR Images: Computerized Characterization for Image-based Prognostic Markers
Neha Bhooshan, Maryellen L. Giger, Sanaz A. Jansen, Hui Li, Li Lan, and Gillian M. Newstead
Radiology 2010;254 680-690

Link to Journal

Study results show that our MR imaging computer-aided diagnosis algorithm, with use of a combination of computer-extracted MR imaging kinetic and morphologic features, has the potential to be extended to two prognostic tasks: (a) classification of noninvasive (ductal carcinoma in situ) versus invasive (invasive ductal carcinoma [IDC]) lesions and (b) further classification of IDC lesions into lesions with positive lymph nodes (LNs) and lesions with negative LNs.