Multicenter, Double-Blind, Randomized, Intraindividual Crossover Comparison of Gadobenate Dimeglumine and Gadopentetate Dimeglumine for Breast MR Imaging (DETECT Trial)

Multicenter, Double-Blind, Randomized, Intraindividual Crossover Comparison of Gadobenate Dimeglumine and Gadopentetate Dimeglumine for Breast MR Imaging (DETECT Trial)
Laura Martincich, Matthieu Faivre-Pierret, Christian M. Zechmann, Stefano Corcione, Harrie C. M. van den Bosch, Wei-Jun Peng, Antonella Petrillo, Katja C. Siegmann, Johannes T. Heverhagen, Pietro Panizza, Hans-Bjorn Gehl, Felix Diekmann, Federica Pediconi, Lin Ma, Fiona J. Gilbert, Francesco Sardanelli, Paolo Belli, Marco Salvatore, Karl-Friedrich Kreitner, Claudia M. Weiss, and Chiara Zuiani
Radiology 2011; 258 396-408

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Gadobenate dimeglumine (0.1 mmol/kg) results in significantly (P [≤ ] . 0003) greater breast cancer detection rate and significantly (P [≤ ] . 0094) better diagnostic performance relative to that achieved with gadopentetate dimeglumine at an equivalent dose