Why Do Purely Intraductal Cancers Enhance on Breast MR Images?
Christiane K. Kuhl
Radiology 2009;253 281-283

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Diagnosis and treatment of high-grade DCIS can be considered primary prevention of high-grade invasive cancer.

Thus, we have reason to assume that screening with MR imaging would offer a mortality benefit that is higher than that achieved with mammographic screening, not only because of the higher overall sensitivity offered by MR imaging but also because of its bias for selectively depicting prognostically relevant disease

On the basis of the results of the animal study performed by Jansen et al and clinical observations, there is compelling evidence to suggest that the imaging phenotype of a ductal carcinoma in situ (DCIS) lesion (its detectability at mammography and MR imaging, specifically the presence or absence of calcifications on mammograms and the presence or absence of calcifications and the degree of their enhancement on MR images) conveys important biologic information that will be useful when guiding DCIS treatment.

Breast Cancer Screening Results 5 Years after Introduction of Digital Mammography in a Population-based Screening Program

Breast Cancer Screening Results 5 Years after Introduction of Digital Mammography in a Population-based Screening Program
Nico Karssemeijer, Adriana M. Bluekens, David Beijerinck, Jan J. Deurenberg, Matthijs Beekman, Roelant Visser, Ruben van Engen, Annemieke Bartels-Kortland, and Mireille J. Broeders
Radiology 2009;253 353-358

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With the FFDM-CAD combination, detection performance is at least as good as that with SFM. The detection of ductal carcinoma in situ and microcalcification clusters improved with FFDM using CAD, while the recall rate increased.

Results indicate that with full-field digital mammography (FFDM) using computer-aided diagnosis (CAD) and double reading, the detection is as good as that with screen-film mammography, and detection of clustered microcalcifications and ductal carcinoma in situ is improved with FFDM using CAD

Diffusion-weighted MR for Differentiation of Breast Lesions at 3.0 T: How Does Selection of Diffusion Protocols Affect Diagnosis?

Diffusion-weighted MR for Differentiation of Breast Lesions at 3.0 T: How Does Selection of Diffusion Protocols Affect Diagnosis?
Wolfgang Bogner, Stephan Gruber, Katja Pinker, Günther Grabner, Andreas Stadlbauer, Michael Weber, Ewald Moser, Thomas H. Helbich, and Siegfried Trattnig
Radiology 2009;253 341-351

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Optimum ADC determination and DW imaging quality at 3.0 T was found with a combined b value protocol of 50 and 850 sec/mm2. This provided a high accuracy for differentiation of benign and malignant breast tumors

Standardization of b values allows improved inter-study comparisons on the diagnostic accuracy of diffusion-weighted MR breast examinations