Reasons Women at Elevated Risk of Breast Cancer Refuse Breast MR Imaging Screening: ACRIN 6666

Reasons Women at Elevated Risk of Breast Cancer Refuse Breast MR Imaging Screening: ACRIN 6666
Wendie A. Berg, Jeffrey D. Blume, Amanda M. Adams, Roberta A. Jong, Richard G. Barr, Daniel E. Lehrer, Etta D. Pisano, W. Phil Evans III, Mary C. Mahoney, Linda Hovanessian Larsen, Glenna J. Gabrielli, and Ellen B. Mendelson
Radiology 2010; 254:79–87
Link to Journal


Of 1215 women with elevated breast cancer risk who could, according to protocol guidelines, undergo breast MR imaging, only 57.9% agreed to participate
Claustrophobia was the most common reason (in 130 [25.4%] of 512 women) given for non-participation

Primary Breast Carcinoma: Association of Mammographic Calcifications with Osteopontin Expression

Primary Breast Carcinoma: Association of Mammographic Calcifications with Osteopontin Expression
Xiao Wang, Lan Chao, Guohui Ma, Liansheng Chen, Guangchao Jin, Mei Hua, Huiping Liu, Aimei Ouyang, and Xiulan Zhang
Radiology 2010 254:69-78
Link to Journal

Compared with osteopontin (OPN)-negative breast cancers, OPN-positive tumors were more likely to have calcifications, to be spiculated, to have pleomorphic calcifications, to be a triple-negative phenotype, and to be associated with axillary lymph node metastasis

Breast US Computer-aided Diagnosis System: Robustness across Urban Populations in South Korea and the United States

Breast US Computer-aided Diagnosis System: Robustness across Urban Populations in South Korea and the United States
Nicholas P. Gruszauskas, Karen Drukker, Maryellen L. Giger, Ruey-Feng Chang, Charlene A. Sennett, Woo Kyung Moon, and Lorenzo L. Pesce
Radiology 2009;253 661-671

Link to Journal

In general, the breast US computer-aided diagnosis system appears to be effective across different patient populations, but further investigation is warranted

Screening-detected Breast Cancers: Discordant Independent Double Reading in a Population-based Screening Program

Screening-detected Breast Cancers: Discordant Independent Double Reading in a Population-based Screening Program
Solveig Hofvind, Berta M. Geller, Robert D. Rosenberg, and Per Skaane
Radiology 2009;253 652-660

Link to Journal

We found that 23.6% of cancers had a discordant interpretation in prospective independent double-reading examinations performed in a population-based mammography screening program that included dedicated as well as general radiologists

Variability in Interpretive Performance at Screening Mammography and Radiologists' Characteristics Associated with Accuracy

Variability in Interpretive Performance at Screening Mammography and Radiologists' Characteristics Associated with Accuracy
Joann G. Elmore, Sara L. Jackson, Linn Abraham, Diana L. Miglioretti, Patricia A. Carney, Berta M. Geller, Bonnie C. Yankaskas, Karla Kerlikowske, Tracy Onega, Robert D. Rosenberg, Edward A. Sickles, and Diana S. M. Buist
Radiology 2009;253 641-651

Link to Journal

Fellowship training in breast imaging was the only radiologists' characteristic significantly associated with greater sensitivity and higher overall accuracy; however, fellowship-trained radiologists also had significantly higher false-positive rates

When Radiologists Perform Best: The Learning Curve in Screening Mammogram Interpretation

When Radiologists Perform Best: The Learning Curve in Screening Mammogram Interpretation
Diana L. Miglioretti, Charlotte C. Gard, Patricia A. Carney, Tracy L. Onega, Diana S. M. Buist, Edward A. Sickles, Karla Kerlikowske, Robert D. Rosenberg, Bonnie C. Yankaskas, Berta M. Geller, and Joann G. Elmore
Radiology 2009;253 632-640

Link to Journal

Radiologists without fellowship training in breast imaging significantly improved in their interpretation of screening mammograms as they gained clinical experience following residency, while radiologists who received fellowship training in breast imaging did not have this learning curve in clinical practice

Potential Usefulness of Similar Images in the Differential Diagnosis of Clustered Microcalcifications on Mammograms

Potential Usefulness of Similar Images in the Differential Diagnosis of Clustered Microcalcifications on Mammograms
Ryohei Nakayama, Hiroyuki Abe, Junji Shiraishi, and Kunio Doi
Radiology 2009;253 625-631

Link to Journal

The inclusion of similar images can have beneficial effects for many cases in which the status of a lesion is unclear, and it can improve the performance of radiologists in observer studies

Mammography: Yet Another Challenge

Mammography: Yet Another Challenge
Daniel B. Kopans
Radiology 2009;253 587-589

Link to Journal

Miglioretti et al and Elmore et al could determine the criteria that the 18 radiologists with highest interpretive performance used; all radiologists could be taught these criteria to benefit those with lower performance