Decrease in Breast Density in the Contralateral Normal Breast of Patients Receiving Neoadjuvant Chemotherapy: MR Imaging Evaluation

Decrease in Breast Density in the Contralateral Normal Breast of Patients Receiving Neoadjuvant Chemotherapy: MR Imaging Evaluation
Jeon-Hor Chen, Ke Nie, Shadfar Bahri, Chieh-Chih Hsu, Fei-Ting Hsu, Han-Ni Shih, Muqing Lin, Orhan Nalcioglu, and Min-Ying Su
Radiology 2010;255 44-52

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By using three-dimensional MR imaging, we have demonstrated that patients receiving chemotherapy showed reduction of breast density and that the effects were significant after initial treatment with one to two cycles of the doxorubicin and cyclophosphamide regimen

Axillary Lymph Node Metastasis: CA-15-3 and Carcinoembryonic Antigen Concentrations in Fine-Needle Aspirates for Preoperative Diagnosis in Patients wi

Axillary Lymph Node Metastasis: CA-15-3 and Carcinoembryonic Antigen Concentrations in Fine-Needle Aspirates for Preoperative Diagnosis in Patients with Breast Cancer
Min Jung Kim, Byeong-Woo Park, Jong-Baeck Lim, Hyon-Suk Kim, Jin Young Kwak, Soo Jin Kim, Sung Hee Park, Yu-Mee Sohn, Hee Jung Moon, and Eun-Kyung Kim
Radiology 2010;254 691-697

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The mean fine-needle aspiration (FNA) concentrations of carcinoembryonic antigen (CEA) and the breast cancer antigen CA-15-3 in metastatic axillary lymph nodes (ALNs) were higher (both P = .02) than those in nonmetastatic ALNs, and the sensitivity of FNA cytology combined with FNA concentrations of CA-15-3 and CEA was higher (P = .01) than that of FNA cytology alone.

Cancerous Breast Lesions on Dynamic Contrast-enhanced MR Images: Computerized Characterization for Image-based Prognostic Markers

Cancerous Breast Lesions on Dynamic Contrast-enhanced MR Images: Computerized Characterization for Image-based Prognostic Markers
Neha Bhooshan, Maryellen L. Giger, Sanaz A. Jansen, Hui Li, Li Lan, and Gillian M. Newstead
Radiology 2010;254 680-690

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Study results show that our MR imaging computer-aided diagnosis algorithm, with use of a combination of computer-extracted MR imaging kinetic and morphologic features, has the potential to be extended to two prognostic tasks: (a) classification of noninvasive (ductal carcinoma in situ) versus invasive (invasive ductal carcinoma [IDC]) lesions and (b) further classification of IDC lesions into lesions with positive lymph nodes (LNs) and lesions with negative LNs.

Identification, Biopsy, and Treatment of Poorly Understood Premalignant, in Situ, and Indolent Low-Grade Cancers: Are We Becoming Victims of Our Own S

Identification, Biopsy, and Treatment of Poorly Understood Premalignant, in Situ, and Indolent Low-Grade Cancers: Are We Becoming Victims of Our Own Success?
Ferris M. Hall
Radiology 2010;254 655-659
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Imagers are increasingly detecting and performing percutaneous biopsies on borderline, preinvasive, or low-grade cancers that were heretofore rarely identified and that may never progress to meaningful disease.