Tumor Angiogenesis Change Estimated by Using Diffuse Optical Spectroscopic Tomography: Demonstrated Correlation in Women Undergoing Neoadjuvant Chemotherapy for Invasive Breast Cancer?
Marius G. Pakalniskis, Wendy A. Wells, Mary C. Schwab, Heather M. Froehlich, Shudong Jiang, Zhongze Li, Tor D. Tosteson, Steven P. Poplack, Peter A. Kaufman, Brian W. Pogue, and Keith D. Paulsen
Radiology 2011; 259 365-374
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This study results show a correlation between changes in total tissue hemoglobin at diffuse optical spectroscopic tomography and tumor angiogenesis and demonstrate how this noninvasive modality might allow individualization and optimization of neoadjuvant chemotherapy regimens.