Variability in Interpretive Performance at Screening Mammography and Radiologists' Characteristics Associated with Accuracy

Variability in Interpretive Performance at Screening Mammography and Radiologists' Characteristics Associated with Accuracy
Joann G. Elmore, Sara L. Jackson, Linn Abraham, Diana L. Miglioretti, Patricia A. Carney, Berta M. Geller, Bonnie C. Yankaskas, Karla Kerlikowske, Tracy Onega, Robert D. Rosenberg, Edward A. Sickles, and Diana S. M. Buist
Radiology 2009;253 641-651

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Fellowship training in breast imaging was the only radiologists' characteristic significantly associated with greater sensitivity and higher overall accuracy; however, fellowship-trained radiologists also had significantly higher false-positive rates

When Radiologists Perform Best: The Learning Curve in Screening Mammogram Interpretation

When Radiologists Perform Best: The Learning Curve in Screening Mammogram Interpretation
Diana L. Miglioretti, Charlotte C. Gard, Patricia A. Carney, Tracy L. Onega, Diana S. M. Buist, Edward A. Sickles, Karla Kerlikowske, Robert D. Rosenberg, Bonnie C. Yankaskas, Berta M. Geller, and Joann G. Elmore
Radiology 2009;253 632-640

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Radiologists without fellowship training in breast imaging significantly improved in their interpretation of screening mammograms as they gained clinical experience following residency, while radiologists who received fellowship training in breast imaging did not have this learning curve in clinical practice

Potential Usefulness of Similar Images in the Differential Diagnosis of Clustered Microcalcifications on Mammograms

Potential Usefulness of Similar Images in the Differential Diagnosis of Clustered Microcalcifications on Mammograms
Ryohei Nakayama, Hiroyuki Abe, Junji Shiraishi, and Kunio Doi
Radiology 2009;253 625-631

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The inclusion of similar images can have beneficial effects for many cases in which the status of a lesion is unclear, and it can improve the performance of radiologists in observer studies

Mammography: Yet Another Challenge

Mammography: Yet Another Challenge
Daniel B. Kopans
Radiology 2009;253 587-589

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Miglioretti et al and Elmore et al could determine the criteria that the 18 radiologists with highest interpretive performance used; all radiologists could be taught these criteria to benefit those with lower performance

Why Do Purely Intraductal Cancers Enhance on Breast MR Images?
Christiane K. Kuhl
Radiology 2009;253 281-283

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Diagnosis and treatment of high-grade DCIS can be considered primary prevention of high-grade invasive cancer.

Thus, we have reason to assume that screening with MR imaging would offer a mortality benefit that is higher than that achieved with mammographic screening, not only because of the higher overall sensitivity offered by MR imaging but also because of its bias for selectively depicting prognostically relevant disease

On the basis of the results of the animal study performed by Jansen et al and clinical observations, there is compelling evidence to suggest that the imaging phenotype of a ductal carcinoma in situ (DCIS) lesion (its detectability at mammography and MR imaging, specifically the presence or absence of calcifications on mammograms and the presence or absence of calcifications and the degree of their enhancement on MR images) conveys important biologic information that will be useful when guiding DCIS treatment.

Breast Cancer Screening Results 5 Years after Introduction of Digital Mammography in a Population-based Screening Program

Breast Cancer Screening Results 5 Years after Introduction of Digital Mammography in a Population-based Screening Program
Nico Karssemeijer, Adriana M. Bluekens, David Beijerinck, Jan J. Deurenberg, Matthijs Beekman, Roelant Visser, Ruben van Engen, Annemieke Bartels-Kortland, and Mireille J. Broeders
Radiology 2009;253 353-358

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With the FFDM-CAD combination, detection performance is at least as good as that with SFM. The detection of ductal carcinoma in situ and microcalcification clusters improved with FFDM using CAD, while the recall rate increased.

Results indicate that with full-field digital mammography (FFDM) using computer-aided diagnosis (CAD) and double reading, the detection is as good as that with screen-film mammography, and detection of clustered microcalcifications and ductal carcinoma in situ is improved with FFDM using CAD

Diffusion-weighted MR for Differentiation of Breast Lesions at 3.0 T: How Does Selection of Diffusion Protocols Affect Diagnosis?

Diffusion-weighted MR for Differentiation of Breast Lesions at 3.0 T: How Does Selection of Diffusion Protocols Affect Diagnosis?
Wolfgang Bogner, Stephan Gruber, Katja Pinker, Günther Grabner, Andreas Stadlbauer, Michael Weber, Ewald Moser, Thomas H. Helbich, and Siegfried Trattnig
Radiology 2009;253 341-351

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Optimum ADC determination and DW imaging quality at 3.0 T was found with a combined b value protocol of 50 and 850 sec/mm2. This provided a high accuracy for differentiation of benign and malignant breast tumors

Standardization of b values allows improved inter-study comparisons on the diagnostic accuracy of diffusion-weighted MR breast examinations