Risk of Upgrade of Atypical Ductal Hyperplasia after Stereotactic Breast Biopsy: Effects of Number of Foci and Complete Removal of Calcifications
Jennifer R. Kohr, Peter R. Eby, Kimberly H. Allison, Wendy B. DeMartini, Robert L. Gutierrez, Sue Peacock, and Constance D. Lehman
Radiology 2010; 255 723-730
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Ultimately, despite the theoretically improved accuracy of 9- and 11-gauge vacuum-assisted breast biopsy needles and the risk stratification performed on the basis of histopathologic and mammographic criteria, we were unable to identify a subpopulation of patients with atypical ductal hyperplasia who could safely avoid surgical excision
The upgrade rate is significantly higher when ADH involves at least three foci. Surgical excision is recommended even when ADH involves fewer than three foci and all mammographic calcifications have been removed, because the upgrade rate is 12%
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