Early-Stage Invasive Breast Cancers: Potential Role of Optical Tomography with US Localization in Assisting Diagnosis
Quing Zhu, Poornima U. Hegde, Andrew Ricci, Jr, Mark Kane, Edward B. Cronin, Yasaman Ardeshirpour, Chen Xu, Andres Aguirre, Scott H. Kurtzman, Peter J. Deckers, and Susan H. Tannenbaum
Radiology 2010;256 367-378
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Purpose: To investigate the potential role of optical tomography in the near-infrared (NIR) spectrum with ultrasonographic (US) localization as a means of differentiating early-stage cancers from benign lesions of the breast.
We showed that intrinsic angiogenesis (tHb - total hemoglobin concentration) contrast imaged by using the NIR technique with US holds promise as an adjunct to mammography and US for distinguishing early-stage invasive breast cancers from benign lesions
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