Diffusion-weighted MR Imaging: Pretreatment Prediction of Response to Neoadjuvant Chemotherapy in Patients with Breast Cancer
Sang Hee Park, Woo Kyung Moon, Nariya Cho, In Chan Song, Jung Min Chang, In-Ae Park, Wonshik Han, and Dong-Young Noh
Radiology 2010;257 56-63
Link to Journal
Our results show that in patients with breast cancer, the pretreatment apparent diffusion coefficients of patients who responded to neoadjuvant chemotherapy are significantly lower than those of patients who did not respond to neoadjuvant chemotherapy.
Patients with breast cancer and a low pretreatment ADC tended to respond better to chemotherapy. Prediction of response to neoadjuvant chemotherapy with DW MR imaging might help physicians individualize treatments and avoid ineffective chemotherapy
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